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What is Down Syndrome? Down syndrome, also known as Down's syndrome, trisomy 21, or (formerly) mongolism is a condition that is caused due to the presence of an extra copy of chromosome 21 in the cells of the body. Due to this extra genetic material it causes mental disability, various health problems, and also some unique physical features.

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According to Wikipedia.org - "Down syndrome (DS or DNS), also known as trisomy 21, is a genetic disorder caused by the presence of all or part of the third copy of chromosome 21. It is typically associated with physical growth delays, mild to moderate intellectual disability, and characteristic facial features.

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Down Syndrome - StatPearls - NCBI Bookshelf HHS Vulnerability Disclosure Down syndrome was first described by an English physician John Langdon Down in 1866, but its association with chromosome 21 was established almost 100 years later by Dr. Jerome Lejeune in Paris.

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Down syndrome affects about one out of every 700 babies born in the United States, which is approximately 6,000 live births per year. More than 200,000 people in the United States are currently living with this condition. The incidence of Down syndrome has remained stable within the population.

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Down syndrome is a genetic condition, but it isn't hereditary. Neither trisomy 21 nor mosaicism is inherited from a parent. These cases of Down syndrome are the result of a random cell division.

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Infants with Down syndrome have a 62-fold higher rate of pneumonia, especially in the first year after birth, than do infants without Down syndrome, for example. 2 Hypothyroidism. The thyroid is a gland that makes hormones the body uses to regulate things such as temperature and energy.

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While the notion of animals with Down syndrome is a myth, apes are the one animal that seems to sometimes exhibit a genetic defect at least comparable to Down syndrome. Apes have 24 pairs of chromosomes as opposed to humans' 23 and some apes have been diagnosed with having an extra copy of chromosome 22, which is similar to chromosome 21 in humans.

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The symptoms of Down syndrome vary from person to person, and people with Down syndrome may have different problems at different times of their lives. Physical Symptoms. Common physical signs of Down syndrome include 1, 2: Decreased or poor muscle tone; Short neck, with excess skin at the back of the neck; Flattened facial profile and nose

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Down syndrome (sometimes called Down's syndrome) is a condition in which a child is born with an extra copy of their 21st chromosome — hence its other name, trisomy 21. This causes physical.

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Down syndrome is a genetic disorder caused when abnormal cell division results in an extra full or partial copy of chromosome 21. This extra genetic material causes the developmental changes and physical features of Down syndrome. Down syndrome varies in severity among individuals, causing lifelong intellectual disability and developmental delays.

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Poor muscle tone or loose joints Shorter in height as children and adults How Many Babies are Born with Down Syndrome? Down syndrome remains the most common chromosomal condition diagnosed in the United States. Each year, about 6,000 babies born in the United States have Down syndrome.

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[ Read summary ] Researchers estimated that in 2008 about 1 out of every 1,200 people (children, teens, and adults) living in the United States had Down syndrome. This means that in 2008 about 250,700 children, teens, and adults were living with Down syndrome in the United States. [ Read summary ]

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People who have Down syndrome have learning difficulties, mental disability, a characteristic facial appearance, and poor muscle tone (hypotonia) in infancy. Individuals with Down syndrome also have an increased risk for having heart defects, digestive problems such as gastroesophageal reflux or celiac disease, and hearing loss.

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Mosaic Down syndrome: This type of Down syndrome occurs when there is a mixture of some cells in the body with trisomy 21 and some cells in the body without an extra chromosome 21. The symptoms can be similar to symptoms of full trisomy 21, but sometimes the effects are milder. It is seen in about 2% of people diagnosed with Down syndrome.

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1 Sep 2022. 4:10 PM ET. By Emily Underwood. A hormone that boosts memory in mice may hold promise for adults with Down syndrome. Halfpoint/iStock. New research with mice—and a small human trial—raises the prospect of treatments that could improve learning difficulties in people with Down syndrome. Though still preliminary, the work may.

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Trisomy 21: In this type of Down syndrome, each cell in the body has three separate copies of chromosome 21 instead of the usual 2 copies. About 95% of people with Down syndrome have this type. Translocation Down syndrome: This occurs when an extra part or a whole extra chromosome 21 is present, but it is attached to a different chromosome ("trans-located") rather than being a separate.